Personally, if you have a Postfix guide and it's setup now, I'd go with 
that.  I have my home system setup with Postfix, MySQL, Squirrelmail, 
SpamAssassin and CourierIMAP (POP & IMAP) doing virtual hosting.  At 
work, I use qmail with a virtual hosting setup.

qmail is quite a bit more complex than Postfix, though they are both 
very powerful. As mentioned below, avoid sendmail like the plague.

~ Tony


Mike Garfias wrote:
> Postfix is what I run.  Its relatively easy to set up for basic stuff.  Its
> also very very flexible so you can do more complex stuff.
> 
> I'd also look at Exim if your expected setup is pretty simple
> 
> Avoid sendmail like the plague.
> 
> I've dealt with qmail in the past... its weird.  It works well, but not
> exactly an easy setup.
> George Toft spoke forth with the blessed manuscript:
>> Previous post lost its way...
>>
>> The time has come for me to implement my own mail server that can handle 
>> virtual domains.  I have a postfix book, and postfix looks pretty easy.
>>
>> Anyone have any recommendations for SMTP server that is easy to install 
>> and admin?  Platform is Fedora Core 2.
>>
>> -- 
>> George
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