No problem, follow these steps:
1) Create a new blank sheet
2) Go to the source sheet
3) Select the block you wish to transpose
4) Edit|Copy
5) Select the new blank sheet
6) Select Cell A1
7) Edit|Paste Special
8) Click the transpose checkbox
9) OK

This will copy your data into a new sheet with columns and rows transposed.

Josef Lowder wrote:
> Is there any way to change a horizontal oocalc spreadsheet
> to a vertical layout -- i.e. so that all existing horizontal columns
> would be converted to become vertical rows, and all data
> in each column and row is rearranged accordingly?
> 
> 
> 
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