Looks like it's just creating a generic usb serial port, so I'd presume you need to tell the program your hardware device serial speed, flow control, bits, etc and have it misconfigured currently it's erroring in that seeing bits it expects returned. Being legacy serial vs like a hardware sdr, this is not negotiated but rather needs set for your device requirements usually, but depending on your hardware that might not always be the same.
Also make sure the port is actually running on /dev/ttyUSB0 and not USB1 or other, I've had this happen if a cable gets yanked or wiggled causing the device to reset too quickly and is already in use. Check using "dmesg | grep usbTTY" to make sure the number.
-mb